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Radiomics--Foundation Fusion for Interpretable RCC Classification: Internal Benchmarking and Exploratory External Transfer

arXiv · AI, language, vision and robotics · article · Sep 22, 2026 · UTC

Accurate preoperative subtype classification of renal cell carcinoma (RCC) from contrast-enhanced CT remains clinically challenging because clear cell RCC (ccRCC) and non-clear cell RCC often show overlapping imaging appearances. This study evaluates whether foundation representations reduce reliance on handcrafted radiomics, or whether radiomics remains complementary for interpretable tumour characterisation. We compared radiomics, conventional CNN features, MedicalNet-pretrained features, MedVAE representations, and fusion variants for binary ccRCC classification on KiTS23, reporting area un

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