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JAREX: An Acquisition Function for Multi-Objective Algorithmic Process Characterization

arXiv · AI, language, vision and robotics · article · Sep 21, 2026 · UTC

Pharmaceutical process characterization is central to Quality by Design because it defines how variations in process parameters affect the ability to meet product quality specifications, thereby supporting proven acceptable ranges and robust manufacturing. In practice, however, characterization still relies largely on factorial design of experiments (DOE) approaches, which are inefficient for resolving multivariate pass/fail boundaries in higher-dimensional spaces. While Bayesian optimization has transformed process optimization, adaptive methods for multi-objective process characterization re

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