SOURCE-LINKED INTELLIGENCE

Forecasting Intrathecal Tracer Enhancement from Pre-Contrast Brain MRI: Direct Regression versus Flow Matching

arXiv · AI, language, vision and robotics · article · Sep 17, 2026 · UTC

Intrathecal contrast-enhanced MRI tracks how a cerebrospinal-fluid tracer spreads through the brain, but requires repeated scans over 24--48\,h. Forecasting enhancement from a pre-contrast scan could one day help select patients for intrathecal drug treatment and plan their dose. We ask how much of the enhancement at a given time can be predicted from the pre-contrast scan and the elapsed time alone. Training on 104 patients, we compared direct image-to-image regression (I2I) with conditional flow matching (CFM) using the same 3D U-Net and protocol, and tested on 23 held-out patients and 51 ex

Read original source ↗ Open in workspace

recordType

paper

region

Global