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MSR-IVA: Masked Structural Residual Independent Vector Analysis for State-Aware Fusion of Structural MRI and Dynamic Functional Network Connectivity

arXiv · AI, language, vision and robotics · article · Aug 25, 2026 · UTC

Multimodal fusion of structural MRI (sMRI) and dynamic functional network connectivity (dFNC) can reveal how brain structure relates to changing functional states. When the same structural latent representation is coupled with multiple states, applying independent vector analysis (IVA) separately to each state can produce unrelated structural decompositions, while forcing identical decompositions may suppress state-specific relationships. In addition, not every subject expresses every dynamic state. We propose masked structural residual IVA (MSR-IVA), a state-aware framework that combines a sh

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