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FAN-LoRA: A Fourier-Adaptive Nonlinear Low-Rank Adaptor for Medical Foundation Model Domain Adaptation

arXiv · AI, language, vision and robotics · article · Aug 27, 2026 · UTC

The advent of vision foundation models, notably the Segment Anything Model (SAM), has catalyzed significant advancements in natural image segmentation. However, their direct transfer to medical imaging remains severely bottlenecked by profound domain gaps, such as cross-modality and cross-center shifts. Existing Parameter-Efficient Fine-Tuning (PEFT) methods facilitate the adaptation of SAM to medical domains; nevertheless, they frequently suffer from performance degradation under severe distribution shifts. This vulnerability primarily stems from the implicit entanglement of heterogeneous fre

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