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BrainDiff: Longitudinal Report Generation for Multimodal Brain MRI

arXiv · AI, language, vision and robotics · article · Sep 1, 2026 · UTC

Neuroradiologists rarely read a brain MRI in isolation, yet automated brain-MRI report generation has been built almost entirely for single studies. Temporal analysis has been explored on chest radiography and chest CT, but to our knowledge, longitudinal reporting for brain MRI, where interval change is often subtle and spatially distributed, remains unaddressed. We present BrainDiff, the first longitudinal vision-language system for brain MRI. BrainDiff outperforms both frontier general-purpose and single-study neuroimaging models on the same patient pairs. Moreover, BrainDiff retains 91% of

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First collected: 2026-09-21T06:21:59.299Z. This is not the publication date.